Summary Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a worldwide pandemic with millions infected. The immune responses of human body to the severe COVID-19 have been well studied, and a number of antibody-based assays have been developed for serological studies. Moreover, the study of the neutralizing antibody that targets at a special structural protein of the SARS-CoV-...
What is cTnI? Troponin (Tn) is a complex of three regulatory proteins (C, I, T) that is integral to muscle contraction in skeletal muscle and cardiac muscle, but not smooth muscle. However, TnT and TnI in cardiac muscle are presented by forms different from those in skeletal muscles. Distribution of cTnI during AMI When AMI and myocardial cell damage occurs: The free cTnI in cardiac muscle is rele...
Vitamin D and Bone Health What is Vitamin D? Vitamin D, first identified as a vitamin early in the 20th century, is now recognized as a prohormone. It is a group of fat-soluble secosteroids that is naturally present in very few foods, responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, and many other biological effects. Vitamin D plays an important ro...
Getein PCT solution -- Sepsis diagnosis Sepsis, defined as a life-threatening organ dysfunction caused by a dysregulated host-response to infection, is a worldwide highly prevalent syndrome, associated with significant morbidity and mortality[1]. Important aspects of sepsis management are early diagnosis in the first few hours of triage[2]. However, the correct diagnosis and differentiation...
World Sepsis Day is a Global Sepsis Alliance initiative that started in 2012 and occurs every year on September 13th with events held all over the world to raise awareness about sepsis. World Sepsis Day is important because it is an opportunity for people worldwide to unite in the fight against sepsis which accounts for at least 8 million deaths worldwide annually [1]. Yet, depending on the...
Preface Influenza is a seasonal respiratory illness that occurs annually, usually peaking in winter. It affects 5-10% of adults and 20-30% of children each year.[1] This common, yet serious, infectious disease, represente a significant threat to public health. Globally, annual influenza epidemics are estimated to result in about 3 to 5 million cases of severe illness, millions of hospita...
Mild or moderate COVID-19 lasts about two weeks for most people. But others experience lingering health problems even after the fever and cough go away and they are no longer testing positive for the illness, which is known as post-COVID conditions (PCC) or long COVID. The World Health Organization has developed a definition for long COVID as coronavirus symptoms that persist or return three month...
Thyroid Problems & Disease: Types and Causes Prevalence of Thyroid Dysfunction Thyroid dysfunction is a common endocrine disorder worldwide. The prevalence varies across different populations and regions. 2 billion people or 30% of the world’s population are still at risk of iodine deficiency 20 million Americans are estimated to have some form of thyroid disease according to the ...